Gonorrhoea is a disease caused by the bacterium called Neisseria gonorrhoea. The infection is spread by unprotected vaginal, oral and anal sex.
Symptoms can include a thick green or yellow discharge from sexual organs, pain when urinating and bleeding between periods. Often the person has no symptoms, however, but can still easily spread the disease to others.
Untreated infection can lead to infertility, pelvic inflammatory disease and can be passed on to a child during pregnancy.
Gonorrhoea is the second most common sexually transmitted infection in England and cases are soaring.
Dame Sally Davies has written to all GPs and pharmacies to ensure they are prescribing the correct drugs after the rise of "super-gonorrhoea" in Leeds.
Her warning comes after concerns were raised that some patients were not getting both of the antibiotics needed to clear the infection.
Sexual health doctors said gonorrhoea was "rapidly" developing resistance.
A highly drug-resistant strain of gonorrhoea was detected in the north of England in March.
That strain is able to shrug off the antibiotic azithromycin, which is normally used alongside another drug, ceftriaxone.
In her letter, the chief medical officer said: "Gonorrhoea is at risk of becoming an untreatable disease due to the continuing emergence of antimicrobial resistance."
BBCNews
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